丰满老妇高潮一级A片,特级婬片A片AAA毛片咕噜咕噜 ,特级BBBBBBBBB视频,国产黄色免费网站
最近搜索：細胞培養(yǎng) 微生物學 分子生物 生物化學
首頁>>免疫學>>一抗>>I型膠原蛋白/膠原蛋白1/1型膠原蛋白/I型膠原a1抗體
I型膠原蛋白/膠原蛋白1/1型膠原蛋白/I型膠原a1抗體
  • 產(chǎn)品貨號：
    BN41633R
  • 中文名稱：
    I型膠原蛋白/膠原蛋白1/1型膠原蛋白/I型膠原a1抗體
  • 英文名稱：
    Rabbit anti-Collagen I Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

    備注

  • BN41633R-50ul

    50ul

    ￥1486.00

    交叉反應：Human,Mouse,Rat,Rabbit(predicted:Chicken,Dog,Cow,Sheep) 推薦應用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

  • BN41633R-100ul

    100ul

    ￥2360.00

    交叉反應：Human,Mouse,Rat,Rabbit(predicted:Chicken,Dog,Cow,Sheep) 推薦應用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

  • BN41633R-200ul

    200ul

    ￥3490.00

    交叉反應：Human,Mouse,Rat,Rabbit(predicted:Chicken,Dog,Cow,Sheep) 推薦應用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱Collagen I
中文名稱I型膠原蛋白/膠原蛋白1/1型膠原蛋白/I型膠原a1抗體
別    名Collagen type I; Alpha 1 type I collagen; Alpha 2 type I collagen; COL1A1; COL1A2; Collagen I alpha 1 polypeptide; Collagen I alpha 2 polypeptide; Collagen Of Skin Tendon And Bone; Collagen Type 1; Collagen type I alpha 1; Collagen type I alpha 2; OI4; Osteogenesis Imperfecta Type IV; Pro alpha 1(I) collagen; Type I procollagen; CO1A1_HUMAN.  



研究領(lǐng)域腫瘤  細胞生物  免疫學  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Human, Mouse, Rat, Rabbit,  (predicted: Chicken, Dog, Cow, Sheep, )
產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量130kDa
細胞定位細胞外基質(zhì) 分泌型蛋白 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Collagen I:1051-1150/1464 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.

Function:
Type I collagen is a member of group I collagen (fibrillar forming collagen).

Subunit:
Trimers of one alpha 2(I) and two alpha 1(I) chains. Interacts with MRC2. Interacts with TRAM2. Subcellular Location : Secreted, extracellular space, extracellular matrix.

Subcellular Location:
Secreted, extracellular space, extracellular matrix.

Tissue Specificity:
Forms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite.

Post-translational modifications:
Proline residues at the third position of the tripeptide repeating unit (G-X-P) are hydroxylated in some or all of the chains. Proline residues at the second position of the tripeptide repeating unit (G-P-X) are hydroxylated in some of the chains.
O-linked glycan consists of a Glc-Gal disaccharide bound to the oxygen atom of a post-translationally added hydroxyl group.

DISEASE:
Defects in COL1A1 are the cause of Caffey disease (CAFFD) [MIM:114000]; also known as infantile cortical hyperostosis. Caffey disease is characterized by an infantile episode of massive subperiosteal new bone formation that typically involves the diaphyses of the long bones, mandible, and clavicles. The involved bones may also appear inflamed, with painful swelling and systemic fever often accompanying the illness. The bone changes usually begin before 5 months of age and resolve before 2 years of age.
Defects in COL1A1 are a cause of Ehlers-Danlos syndrome type 1 (EDS1) [MIM:130000]; also known as Ehlers-Danlos syndrome gravis. EDS is a connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity. EDS1 is the severe form of classic Ehlers-Danlos syndrome.
Defects in COL1A1 are the cause of Ehlers-Danlos syndrome type 7A (EDS7A) [MIM:130060]; also known as autosomal dominant Ehlers-Danlos syndrome type VII. EDS is a connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity. EDS7A is marked by bilateral congenital hip dislocation, hyperlaxity of the joints, and recurrent partial dislocations.
Defects in COL1A1 are a cause of osteogenesis imperfecta type 1 (OI1) [MIM:166200]. A dominantly inherited connective tissue disorder characterized by bone fragility and blue sclerae. Osteogenesis imperfecta type 1 is non-deforming with normal height or mild short stature, and no dentinogenesis imperfecta.
Defects in COL1A1 are a cause of osteogenesis imperfecta type 2 (OI2) [MIM:166210]; also known as osteogenesis imperfecta congenita. A connective tissue disorder characterized by bone fragility, with many perinatal fractures, severe bowing of long bones, undermineralization, and death in the perinatal period due to respiratory insufficiency.
Defects in COL1A1 are a cause of osteogenesis imperfecta type 3 (OI3) [MIM:259420]. A connective tissue disorder characterized by progressively deforming bones, very short stature, a triangular face, severe scoliosis, grayish sclera, and dentinogenesis imperfecta.
Defects in COL1A1 are a cause of osteogenesis imperfecta type 4 (OI4) [MIM:166220]; also known as osteogenesis imperfecta with normal sclerae. A connective tissue disorder characterized by moderately short stature, mild to moderate scoliosis, grayish or white sclera and dentinogenesis imperfecta.
Genetic variations in COL1A1 are a cause of susceptibility to osteoporosis (OSTEOP) [MIM:166710]; also known as involutional or senile osteoporosis or postmenopausal osteoporosis. Osteoporosis is characterized by reduced bone mass, disruption of bone microarchitecture without alteration in the composition of bone. Osteoporotic bones are more at risk of fracture.
Note=A chromosomal aberration involving COL1A1 is found in dermatofibrosarcoma protuberans. Translocation t(17;22)(q22;q13) with PDGF.

Similarity:
Belongs to the fibrillar collagen family.
Contains 1 fibrillar collagen NC1 domain.
Contains 1 VWFC domain.

SWISS:
P02452

Gene ID:
1277

Database links:
Entrez Gene: 1277 Human

·    Entrez Gene: 12842 Mouse

·    Entrez Gene: 100008952 Rabbit

·    Entrez Gene: 29393 Rat

·    Omim: 120150 Human

·    SwissProt: P02453 Cow

·    SwissProt: O46392 Dog

·    SwissProt: P02452 Human

·    SwissProt: P11087 Mouse

·    SwissProt: P02454 Rat

·    Unigene: 172928 Human

·    Unigene: 277735 Mouse

·    Unigene: 107239 Rat




Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


小黄书在线观看www网页 | 中国四川农村自拍的一级免费片 | 黄 色 成 人 视 频 | 蜜臀AV999无码精品国产专区 | 成年人电影黄色国产视频 | 亚洲精品乱码爱爱操麻豆 | H肉动漫无码AV在线亚洲一区 | 免费白丝jk爆 乳在线观看 | 国产日皮视频在线观看 | 无码区免费看一级毛片A片 影音先锋中文字幕在线观看 | 亚洲丰满少妇A级毛片 | 人人夸人人干人人爽人人操 | 成人爆乳专区一区二区 | 国产主播在线观看一区二区不卡av | 91久久精品一区二区别 | 欧中国美乱婬交换粗大 | 国产色情无码一区二区百度云 | 在线观看黄色视频大全 | 17c网站在线免费观看 | 少妇激情一区二区三区久久大香香 | www.91.xhs.小黄书成人网站 | 毛片大全在线观看 | 本田岬无码破解精品一区 | 九一国产原创中文免费播 | 91丝袜放荡丝袜脚交 | 最新中文字幕在线 | 国产一区二区三区在线 | 一级内射片在线网站观看 | 十五分钟高清无码视频 | 中文字幕无码黄色视频 | 蜜桃视频在线观看无码 | 色婷婷一区二区三区久久午夜成人 | 久久99嫩草熟妇人妻蜜臀 | 午夜国产精品秘 入口无码 国产成人无码综合亚洲日韩 | 7777理论片午夜无码 | 国产黄色视频网站 | 91小视频在线观看 | 日本一级婬片A片AAA毛多多 | 强伦轩一区二区三区免费看 | 日本高清无码在线观看 | 国产69精品久久久久久 |