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磷酸化蛋白激酶GCN2蛋白抗體

產(chǎn)品貨號(hào)：

BN40868R
中文名稱：

磷酸化蛋白激酶GCN2蛋白抗體
英文名稱：

Rabbit anti-phospho-GCN2 (Thr667) Polyclonal antibody
品牌：

Biorigin

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BN40868R-100ul

100ul

￥2470.00

交叉反應(yīng)：Mouse,Rat(predicted:Human,Dog,Cow,Horse) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱	phospho-GCN2 (Thr667)
中文名稱	磷酸化蛋白激酶GCN2蛋白抗體
別名	GCN2 (phospho T667); p-GCN2 (phospho T667); EIF2AK4; Eukaryotic Translation Initiation Factor 2-alpha kinase 4; GCN2-like protein; KIAA1338; E2AK4_HUMAN; Eif2ak4; Eukaryotic Translation Initiation Factor 2 alpha kinase 4; GCN2; GCN2 eIF2alpha kinase; GCN2-like protein; MGCN2.
產(chǎn)品類型	磷酸化抗體
研究領(lǐng)域	細(xì)胞生物神經(jīng)生物學(xué)
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應(yīng)	Mouse, Rat, (predicted: Human, Dog, Cow, Horse, )
產(chǎn)品應(yīng)用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	181kDa
細(xì)胞定位	細(xì)胞漿
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated Synthesised phosphopeptide derived from human GCN2 around the phosphorylation site of Thr667:PG(p-T)PP
亞型	IgG
純化方法	affinity purified by Protein A
儲(chǔ) 存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	GCN2 belongs to a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor 2 to downregulate protein synthesis in response to varied cellular stresses. Tissue Specificity: Widely expressed. Post-translational modifications: Autophosphorylated on threonine residues. Similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily. Contains 2 protein kinase domains. Contains 1 RWD domain. SWISS: Q9P2K8 Gene ID: 440275 Database links: Entrez Gene: 440275 Human Entrez Gene: 27103 Mouse Entrez Gene: 114859 Rat Omim: 609280 Human SwissProt: Q9P2K8 Human SwissProt: Q9QZ05 Mouse Unigene: 656673 Human Unigene: 217616 Mouse Unigene: 8333 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. GCN2蛋白的作用；可能是將短期記憶變成長期記憶的一個(gè)主控調(diào)節(jié)因子， GCN2蛋白在長期記憶形成中功能的發(fā)現(xiàn)將可能幫助研究人員開發(fā)出提高記憶力喪失的病人提高記憶力。